An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis
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چکیده
منابع مشابه
Alteration in the hypothalamic-pituitary-ovarian axis in depressed women.
BACKGROUND Stress and corticotropin-releasing hormone inhibit the reproductive axis. We hypothesized that reproductive axis hormone secretion, particularly luteinizing hormone secretion, is inhibited in women with depression, similar to what has been observed to be caused by stress in numerous species. METHODS Blood samples were collected every 10 minutes for 12 hours in 25 untreated premenop...
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In this study the expression of GnRH, FSH, LH, ER-α, ER-β, and PR receptors was examined in uterine myomas of women in reproductive and perimenopausal age. In cases of GnRH and tropic hormones a membranous and cytoplasmic immunohistochemical reaction was detected, in cases of ER-α and PR the reaction was located in cell nucleus, and in the case of ER-β it manifested also a cytoplasmic location....
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This article summarizes the studies of the mechanism of electroacupuncture (EA) in the regulation of the abnormal function of hypothalamic-pituitary-ovarian axis (HPOA) in our laboratory. Clinical observation showed that EA with the effective acupoints could cure some anovulatory patients in a highly effective rate and the experimental results suggested that EA might regulate the dysfunction of...
متن کاملCognitive correlates of hypothalamic – pituitary – adrenal axis in major depression
www.expert-reviews.com ISSN 1744-6651 © 2011 Expert Reviews Ltd 10.1586/EEM.10.79 Alterations in hypothalamic–pituitary–adrenal (HPA) axis function, such as hypercortisolism and reduced feedback sensitivity, have been a prominent finding in neuroendocrine investigations of major depressive disorder (MDD). Cognitive impairments, particularly those concerning attention, memory and executive funct...
متن کاملThe Role of the Endocannabinoids in Suppression of the Hypothalamic- pituitary-adrenal Axis Activity by Doxepin
Objective(s) The mechanism(s) by which antidepressants regulate the hypothalamic-pituitary-adrenal (HPA) axis remain elusive. The endocannabinoid system (eCBs) which exhibits antidepressant potential, appears to regulate the HPA axis activity. Therefore, we aimed to investigate the role of the eCBs in the action of doxepin including its effect on the HPA axis. Materials and Methods Male Wist...
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2021
ISSN: 2218-273X
DOI: 10.3390/biom11060857